Understanding memory.
My research primarily focused on memory, particularly our autobiographical life memories (“episodic” memories) and how they can be lost in dementia. I particularly focused on acetylcholine, a neurochemical that is important for memory and neuroplasticity.
Photo: Zhen Qin
I am an Adjunct Assistant Professor in the Department of Neuroscience at the Icahn School of Medicine at Mount Sinai. Previously, I was a tenure-track investigator at the Icahn School of Medicine at Mount Sinai and ran a laboratory from 2013 to 2018.
My undergraduate research was at the University of Cambridge, and my Ph.D. was at the University of Oxford where I worked with Matthew Rushworth and David Bannerman. During my postdoctoral work I was a Charles H. Revson Senior Fellow in the Life Sciences (Postdoctoral Fellow) in the laboratory of Mark Baxter, first at the University of Oxford and later at Mount Sinai.
My research focused on memory, particularly autobiographical (“episodic”) memories and how they can be lost in dementia. During my Ph.D. I worked on decision-making. I also specialise in comparative neuroscience, particularly comparing the brains of different primate species, and the use of magnetic resonance imaging (MRI) techniques, including diffusion imagine, functional and structural MRI, in neuroscience.
Selected publications.
Thiebaut de Schotten M, Croxson PL, Mars RB (2019)
Large-scale comparative neuroimaging: Where are we and what do we need? Cortex 118: 188-202. https://doi.org/10.1016/j.cortex.2018.11.028
Froudist-Walsh S, Browning PGF, Young JJ, Murphy KL, Mars RB, Fleysher L, Croxson PL (2018)
Macro-connectomics and microstructure predict dynamic plasticity patterns in the non-human primate brain. eLife 7:e34354. https://doi.org/10.7554/eLife.34354
Croxson PL, Forkel SJ, Cerliani L, Thiebaut de Schotten M (2018)
Structural variability across the primate brain: A cross-species comparison Cerebral Cortex 28: 3829–3841 https://doi.org/10.1093/cercor/bhx244
O’Reilly JX*, Croxson PL*, Jbabdi S, Sallet J, Noonan MP, Mars RB, Browning PG, Wilson CRE, Mitchell AS, Miller KL, Rushworth MFS, Baxter MG (2013)
A causal effect of disconnection lesions on interhemispheric functional connectivity in rhesus monkeys. Proceedings of the National Academy of Sciences 110: 13982-13987 https://doi.org/10.1073/pnas.1305062110
Croxson PL, Browning PGF, Gaffan D, Baxter MG (2012)
Acetylcholine facilitates recovery of episodic memory after brain damage. Journal of Neuroscience 32: 13787-13795 https://doi.org/10.1523/JNEUROSCI.2947-12.2012
Croxson PL, Kyriazis DA, Baxter MG (2011)
Cholinergic modulation of a specific memory function of prefrontal cortex. Nature Neuroscience 14: 1510-1512 https://doi.org/10.1038/nn.2971
Sallet J, Mars RB, Noonan MP, Andersson JL, O’Reilly JX, Jbabdi S, Croxson PL, Jenkinson M, Miller KL, Rushworth MF (2011)
Social network size affects neural circuits in macaques. Science 334: 697-700 https://doi.org/10.1126/science.1210027
Croxson PL*, Walton ME*, O’Reilly JX, Behrens TE, Rushworth MF (2009)
Effort-based cost-benefit valuation and the human brain. Journal of Neuroscience 29: 4531-4541 https://doi.org/10.1523/JNEUROSCI.4515-08.2009
Croxson PL, Johansen-Berg H, Behrens TEJ, Robson MD, Pinsk MA, Gross CG, Richter W, Richter MC, Kastner S, Rushworth MF (2005)
Quantitative investigation of connections of the prefrontal cortex in the human and macaque using probabilistic diffusion tractography. J Neurosci 25: 8854-66 https://doi.org/10.1523/JNEUROSCI.1311-05.2005